It seems like I may have some really good and/or really bad luck.

Blue Dragon -> Sea Dragon (one try)
Staff of Light -> Magi Staff (one try)
any bow -> Morph Bow (cannot do)

Note that one try means I synthesize a whole lot at once and one of them mutated. But I reloadat least 50 times and I can't seem to mutate any bow, and I'm mutating all of my bows. Is the RNG fixed when you enter town or something so you can't reload? Has anyone gotten a mutation upon a reload?

I hope that you are at least in chapter 4 of the story. If so, then you have really bad luck.

My bad I fail hard, I'm not at chapter 4 yet. Reading comprehension, go!

Well, I've also tried doing it before chapter 4 and noticed that it doesn't work xD